Preheat and prepare: Set your oven to 400°F (200°C). Pat the pork tenderloins dry with paper towels.
This helps the spice rub stick and promotes a better sear.
Mix the rub: In a small bowl, stir together salt, pepper, garlic powder, onion powder, smoked paprika, thyme, and red pepper flakes if using.
Season the pork: Rub the tenderloins with Dijon mustard, then coat all over with the spice mix. Press it in so it adheres.
Sear for crust: Heat 1 tablespoon of oil in a large oven-safe skillet over medium-high heat. When shimmering, add the pork and sear on all sides until browned, about 2–3 minutes per side.
Roast to temp: Drizzle the remaining tablespoon of oil in the pan if needed.
Transfer the skillet to the oven. Roast for 10–15 minutes, or until the thickest part reaches 140–145°F (60–63°C) on an instant-read thermometer.
Rest the meat: Move the pork to a cutting board and tent loosely with foil. Rest for 8–10 minutes.
This keeps it juicy and tender.
Finish and serve: Swirl the butter into the hot skillet to melt and pick up browned bits, then spoon over the pork. Slice into 1/2-inch medallions. Serve with lemon wedges and chopped parsley.